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It also includes a lucrative Free Spins feature with multipliers that can reach up to 500x the amount bet. Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which used different investigators and included participants from various geographical areas. This type of heterogeneity which is vital for a pragmatic trial to be valid and reduce bias in results is also essential. However, too much heterogeneity can result in problems with the design of the trial. Pragmatic Play is also a major player on the live casino market, offering an extensive selection of table games like as Blackjack and Roulette in a variety of versions. The live studios of the company in Romania and Malta provide a genuine gambling experience for customers and offer a full suite of virtual betting options. The company also has several game shows which make online gambling exciting and interactive. 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Its software is designed to work with mobile devices and is compatible with multiple languages. Despite its relatively young age, it has already established itself as a leading casino gaming platform. Wolves is one of its latest releases which is a five-reel slot machine that has a high RTP and impressive graphics. Other notable titles include Wolf Gold and Chilli Heat. The purpose of pragmatic trials is to replicate real-life scenarios and gain maximum credibility externally. They are typically ordered by policymakers and practitioners to inform their decisions. They can also be used to determine the causality of an intervention with its outcomes. However, they should not, be used to replace the need for explanation studies. The idea of pragmatism is controversial and there are doubts about whether pragmatic trials can replace tests for explanations or if they should be an addition to them. Schwartz and Lellouch1 suggested the distinction between explanation trials, which validate the clinical or physiological hypothesis and pragmatic trials that inform policy and practice decisions. They also suggested a framework dubbed PRECIS for pragmatic trials.2 The tool was designed to define the characteristics of a practical study, including the recruitment, design, and delivery of the intervention, and follow-up. The number of pragmatic trials is increasing. A recent Medline query using the keywords pragmatic and naturalistic, which was restricted to randomised controlled trials (RCTs) returned 34 articles. They are displayed in red on Figure 2. This indicates that the health sciences community has become more aware of the importance of pragmatism. It is important to remember, however, that the majority were conducted in primary-care settings.